Pharmacological action
Inhibitor of H +-K +-ATPase. The active ingredient Nexium - esomeprazole, S-isomer of omeprazole, decreases the secretion of hydrochloric acid in the stomach by specific inhibition of acid pump in the parietal cells. S-and R-isomer of omeprazole have similar pharmacodynamic activity.
Esomeprazole is a weak base and is activated in the acidic environment of the secretory tubules parietal cells of gastric mucosa, which inhibits the activity of H +-K +-ATPase and thus blocks the final stage of secretion of hydrochloric acid. Nexium inhibits both basal and stimulated gastric secretion.
The action of the drug develops within 1 h after oral administration at a dose of 20 mg or 40 mg. When receiving the drug daily for 5 days at 20 mg 1 time / day average maximum concentration of acid in gastric contents after pentagastrin stimulation is decreased by 90% (when measuring the acid concentration in 6-7 hours after taking the dose on day 5 of therapy).
In patients with symptoms of gastroesophageal reflux disease after 5 days of daily administration Nexium orally at a dose of 20 mg or 40 mg of pH in the stomach for daily monitoring was above 4 for an average of 13 and 17 h, respectively. Among patients taking 20 mg of the drug in the day, the maintenance at the acidity level of pH above 4 for 8, 12 and 16 h was achieved in 76%, 54% and 24%, respectively. For 40 mg esomeprazole, the ratio was 97%, 92% and 56%, respectively.
Analysis of pharmacokinetic data revealed a relationship between acid secretion and the concentration of drug in plasma (the concentration used to assess the parameter AUC).
When you receive 40 mg of the drug in day cure reflux esophagitis occurs in 78% of patients after 4 weeks of therapy and in 93% - after 8 weeks of therapy.
Treatment Nexiumom a dose of 20 mg 2 times / day in combination with appropriate antibiotics for one week leads to the successful eradication of Helicobacter pylori in approximately 90% of patients.
Patients with uncomplicated duodenal ulcer after a week's course of eradication therapy does not require further treatment antisecretory therapy for healing ulcers.
The drug in plasma gastrin level is increased as a result of decreased intragastric acid secretion.
Patients who used antisecretory drugs for a long time, often observed the formation of glandular cysts in the stomach. This phenomenon is due to physiological changes as a result of inhibition of acid secretion. Cysts are benign and tend to disappear.
Due to the fact that esomeprazole is unstable in acidic medium, tablets contain granules of the active substance coated with a stable to the action of gastric juice shell.
Indications
Gastroesophageal reflux disease:
- Treatment of erosive reflux esophagitis;
- Long-term maintenance therapy to prevent relapse in patients with healed esophagitis;
- Symptomatic treatment of gastroesophageal reflux disease.
Eradication Helicobacter pylori (in combination with antibiotic therapy), as well as:
- Treatment of duodenal ulcer associated with Helicobacter pylori;
- Prevention of recurrence of peptic ulcers associated with Helicobacter pylori.
Dosage regimen
For the treatment of erosive reflux esophagitis medication prescribed in a single dose of 40 mg 1 time / day for 4 weeks. Additional 4-week course of therapy is recommended for patients when, after the first course of the disease symptoms persist.
For long-term maintenance treatment of patients with healed esophagitis to prevent relapse of drug prescribe 20 mg 1 time per day.
For the symptomatic treatment of gastroesophageal reflux disease without esophagitis medication prescribed in a dose of 20 mg 1 time per day. If after 4 weeks of treatment the symptoms do not disappear, should undertake further examination of the patient. After removing the symptoms can go to the drug treatment "if necessary", ie take Nexium 20 mg of 1 times / day in the event of symptoms prior to their withdrawal.
For the eradication of Helicobacter pylori, for the treatment of duodenal ulcer associated with Helicobacter pylori, to prevent relapse of peptic ulcers associated with Helicobacter pylori, Nexium prescribe a single dose of 20 mg, amoxicillin - 1 g, clarithromycin - 500 mg. All medications taken 2 times daily for 7 days.
In appointing the drug to patients with impaired renal function dosage adjustment is required. Be wary of the drug in patients with severe renal insufficiency due to limited clinical experience of its use in this category of patients.
In appointing Nexium patients with impaired hepatic function or mild to moderately dosage adjustment is required. Patients with severe hepatic impairment applied dose should not exceed 20 mg / day.
Elderly correction dosing regime is not required.
Tablets should be swallowed whole, washed down with liquid. Pills can not chew or crush. Patients with difficulty swallowing a pill may be dissolved in half a glass of carbonated water, stir up the splitting of tablets and drink a suspension of microgranules immediately or within 30 minutes. Then again, should fill the glass halfway with water, stir and drink residues. You should not use other liquids, as a protective shell microgranules can be dissolved. Do not chew or crush microgranules.
Side effects
In the application of esomeprazole can be expected to rare side effects of the racemic drug (omeprazole). In the conduct of clinical trials esomeprazole such effects have not been described.
In the conduct of clinical studies revealed the following side effects:
From the digestive system: frequent (> 0.01 but <0.1) - abdominal pain, diarrhea, nausea, vomiting, constipation, rarely (> 0.001 but <0.01) - a dry mouth.
From CNS: frequent (> 0.01 but <0.1) - headache, rare (> 0.001 but <0.01) - dizziness.
Dermatological reactions: rare (> 0.001 but <0.01) - dermatitis, pruritus, urticaria.
None of these effects are not dose-dependent manner.
The following adverse effects were observed in the application of the racemic drug (omeprazole) and can be expected also in the application of esomeprazole.
From the central nervous system and peripheral nervous system: paresthesia, somnolence, insomnia, dizziness, reversible mental confusion, anxiety, agitation, depression, hallucinations (mainly in severely ill patients).
From the Endocrine: gynecomastia.
From the digestive system: stomatitis, gastrointestinal candidiasis, increased activity of liver enzymes, encephalopathy in patients with prolonged severe liver disease, hepatitis with (or without), jaundice, liver failure.
The part of the hemopoietic system: leukopenia, thrombocytopenia, agranulocytosis and pancytopenia.
The part of the musculoskeletal system: joint pain, muscle weakness and myalgia.
Dermatological reactions: cyp, photosensitivity, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, alopecia.
Allergic reaction: angioedema, fever, bronchospasm, interstitial nephritis and anaphylactic shock.
Other: general weakness, sweating, peripheral edema, blurred vision, changes in taste and hyponatremia.
Contraindications
- Hypersensitivity to esomeprazole, substituted benzimidazole or other components of the drug.
Pregnancy and lactation
There is currently no data on the use Nexium pregnancy. Appointment of the drug in this period is possible only if the anticipated benefits to the mother outweighs the potential risk to the fetus.
At the present time is unknown, it stands esomeprazole with breast milk, so should not be given Nexium during breastfeeding.
In animal studies did not reveal any negative effects esomeprazole for the development of an embryo or fetus. Introduction of the racemic drug also did not exert any negative impact on the animals during pregnancy, childbirth and the period of postnatal development.
Cautions
Before the appointment of esomeprazole should exclude the possibility of malignancy, since the treatment Nexiumom can lead to smoothing of symptoms and delay diagnosis.
Patients taking the drug over a long period (especially more than a year), should be under regular medical supervision.
Patients who are on the regime "treatment on demand", should be instructed to contact their physician when changing the nature of symptoms. Taking into account the fluctuations in the plasma concentration of esomeprazole in the appointment of the drug in the mode of "treatment on demand", should take into account the interaction of the drug with other drugs.
In appointing Nexium for Helicobacter pylori eradication should be taken into account the possibility of drug interactions for all components of triple therapy. Clarithromycin - a potent inhibitor of CYP3A4, therefore, must consider all contraindications and interactions clarithromycin in the case of patients taking other drugs, is metabolized with the participation of CYP3A4 (eg, cisapride).
Patients with hereditary fructose intolerance, glucose malabsorption or galaktoznoy Sucrase-izomaltaznoy insufficiency should not take this drug.
Use in Pediatrics
We do not recommend the use of drugs in children due to lack of data.
Effects on ability to drive vehicles and management mechanisms
There is no evidence the influence of the drug on the ability to drive vehicles and management mechanisms.
Overdose
There is currently no described cases of overdose. Single dose of 80 mg esomeprazole did not cause any adverse effects.
Treatment: If necessary to symptomatic and supportive therapy. The specific antidote is known. Dialysis is ineffective, because esomeprazole bound to plasma proteins.
Drug Interactions
Effect of esomeprazole on the pharmacokinetics of other drugs
In applying Nexium simultaneously with other drugs, the mechanism of absorption which depends on the acidity of the medium may decrease or increase absorption of other medicines. As well as using other drugs that suppress acid secretion or antacid, treatment of esomeprazole may reduce the absorption of ketoconazole or itraconazole.
The joint application Nexium with drugs, the metabolism of which involved CYP2C19, such as diazepam, citalopram, imipramine, clomipramine, phenytoin, can lead to increased concentrations of these drugs in plasma and demand a reduction of their doses.
In joint admission Nexium and 30 mg of diazepam by 45% decreased clearance of the enzyme-cubstratnogo complex (CYP2C19-diazepam).
In an application Nexium 40 mg 13% increased the residual concentration of phenytoin in the blood plasma of patients with epilepsy (recommended to control the concentration of phenytoin in the blood plasma in the appointment of esomeprazole and its abolition).
In healthy volunteers joint reception with cisapride 40 mg Nexium led to an increase in cisapride AUC and a 32% increase in T1 / 2 cisapride at 31%, but the concentration of cisapride in plasma did not significantly change. Slight lengthening of the interval QT, which occurred in the application of monotherapy with cisapride, while adding Nexium not increased.
In an application Nexium not cause clinically significant changes in pharmacokinetic parameters of amoxicillin, quinidine, and warfarin.
Effect of drugs on the pharmacokinetics of esomeprazole.
In an application Nexium clarithromycin (500 mg 2 times / day) AUC esomeprazole increased by 2 times (Nexium dose adjustment is not required).
Conditions and terms of storage
Drug should be stored in places inaccessible to children, at a temperature below 30 ° C. Do not apply after the expiration date stated on the packaging.
Conditions of supply of pharmacies
The drug is released with a prescription.
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Thursday, December 24, 2009
Wednesday, December 23, 2009
Poor planning: what to do with the rooms of irregular shape?
Rooms of irregular shape, broken ratio, failed niche ... Sometimes lay flat presents us with many surprises. But its shortcomings can be fixed independently, without resorting to radical changes.
Narrow and long
This is too elongated room is that it lacks a cozy corner and there are difficulties with the harmonious arrangement of furniture. How to solve this problem?
If the room has at least two windows along the wall, then we can divide the space into two parts, leaving each of the window. The partition between the two is often better not to do continuous or mobile (eg mobile) to maintain a sense of space. The role of partitioning can perform screen, cabinet or rack with flower plant pots. If the room only one window, then the dark part of you can make the working area with artificial lighting.
Another method of visual correction of space - the podium. It is best to place it in the remote end of the room. A short podium will provide not only a separate zone (it can be done working, equip lounge or sleeper), but also visually shorten the room. The remainder of the room you can place furniture in the usual manner.
There is another great way to make the placement of the desired shape - furniture made to order. Especially good with this task handle sliding door wardrobes, and they cleverly disguised as a wall. Furniture individual project - an excellent option for non-standard facilities (eg, attic).
Small and intimate
Visually, add the volume of small-sized rooms in several ways.
First, you can get rid of the massive door, replacing it with a mobile door-accordion. This will help neutralize the sense of closeness and isolation. Secondly, the correct approach to the selection of furniture. Magic wand for a small and cramped room will be multi-functional furniture "Transformers": retractable bed, sofa with built-in wardrobe, folding table, a bed, a loft with a working area at the bottom, etc. Thirdly, you have to play a hand mirror and transparent surfaces.
How to make the kitchen a cozy
A typical weakness of Khrushchev - a small, but often also disproportionately elongated kitchen. On this and prepare inconvenient and uncomfortable to eat. But a kitchen can be made more comfortable. Just as in the case of a close room, kitchen transformation should start with a change of conventional doors on sliding. Placement of furniture can be varied. For example, a kitchen in one line with high shelves and a table by the window.
Straight lines create the illusion of an elongated cooking a large space. Or give preference to a corner kitchen with folding table.
Interesting design move - folding bar, which can replace the table. And remember: that the room looked cozy and spacious, the interior should be decorated in bright colors.
Read more:
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Narrow and long
This is too elongated room is that it lacks a cozy corner and there are difficulties with the harmonious arrangement of furniture. How to solve this problem?
If the room has at least two windows along the wall, then we can divide the space into two parts, leaving each of the window. The partition between the two is often better not to do continuous or mobile (eg mobile) to maintain a sense of space. The role of partitioning can perform screen, cabinet or rack with flower plant pots. If the room only one window, then the dark part of you can make the working area with artificial lighting.
Another method of visual correction of space - the podium. It is best to place it in the remote end of the room. A short podium will provide not only a separate zone (it can be done working, equip lounge or sleeper), but also visually shorten the room. The remainder of the room you can place furniture in the usual manner.
There is another great way to make the placement of the desired shape - furniture made to order. Especially good with this task handle sliding door wardrobes, and they cleverly disguised as a wall. Furniture individual project - an excellent option for non-standard facilities (eg, attic).
Small and intimate
Visually, add the volume of small-sized rooms in several ways.
First, you can get rid of the massive door, replacing it with a mobile door-accordion. This will help neutralize the sense of closeness and isolation. Secondly, the correct approach to the selection of furniture. Magic wand for a small and cramped room will be multi-functional furniture "Transformers": retractable bed, sofa with built-in wardrobe, folding table, a bed, a loft with a working area at the bottom, etc. Thirdly, you have to play a hand mirror and transparent surfaces.
How to make the kitchen a cozy
A typical weakness of Khrushchev - a small, but often also disproportionately elongated kitchen. On this and prepare inconvenient and uncomfortable to eat. But a kitchen can be made more comfortable. Just as in the case of a close room, kitchen transformation should start with a change of conventional doors on sliding. Placement of furniture can be varied. For example, a kitchen in one line with high shelves and a table by the window.
Straight lines create the illusion of an elongated cooking a large space. Or give preference to a corner kitchen with folding table.
Interesting design move - folding bar, which can replace the table. And remember: that the room looked cozy and spacious, the interior should be decorated in bright colors.
Read more:
yrakellow
sollini
lazzira
emaros
vahhog
qarolla
weralish
garchioss
tigrenwa
bizkalit
hapliza
jivilirge
bastohutta
durenok
roguruez
Monday, December 14, 2009
Order Prozac Online Pharmacy Canada
Buy Now!
Trade name:
Prozac
International name:
Fluoxetine
Group Affiliation:
Antidepressant
Description of the active substance (INN):
Fluoxetine
Dosage form:
Capsules
Pharmacological Effects:
Antidepressive tool, a selective serotonin reuptake inhibitors. It improves mood, reduces tension, anxiety and fear, eliminates dysphoria. Does not cause orthostatic hypotension, sedation, nekardiotoksichen. Persistent clinical effect occurs within 1-2 weeks of treatment.
Indications:
Depression (regardless of the degree of depressive disorder - weak, moderate, severe), bulimia, anorexia, alcoholism, obsessive-compulsive disorder.
Contraindications:
Hypersensitivity, renal failure (CC less than 10 ml / min), expressed liver failure, suicidal tendencies, simultaneous reception of MAO inhibitors (in the previous 2 weeks), pregnancy, laktatsii.C caution. Diabetes mellitus, epileptic syndrome of different genesis and epilepsy (including history), Parkinson's disease, compensated renal and / or hepatic failure, cachexia.
Side effects:
From the nervous system: dizziness, headache, drowsiness or insomnia, lethargy, fatigue, asthenia, tremor, agitation, anxiety, suicidal tendencies (typical of patients with major depressive disorder), mania or hypomania. From the digestive system: loss of appetite, dry mouth or hygrostomia, nausea, diarrhea. Allergic reactions: skin rash, urticaria. Other: increased sweating, weight loss, decreased libido, systemic violations of the lung, kidney or liver, vaskulity.Peredozirovka. Symptoms: nausea, vomiting, a state of excitation, convulsions. Treatment: gastric lavage, the appointment of activated charcoal, in convulsions - anxiolytic LAN (tranquilizers), symptomatic therapy.
Dosage and administration:
Inside, depression starting dose - 20 mg / day 1 time in the morning if necessary, increase the weekly dose of 20 mg / day. The maximum daily dose - 80 mg in 2-3 doses. With bulimia, and for elderly patients - 60 mg in 3 divided doses, with obsessive-compulsive disorder - 20-60 mg / day. Maintenance therapy - 20 mg / day. Course of treatment - 3-4 weeks.
Cautions:
When treating patients with underweight anorectics should take into account the effects of (possible progressive loss of body weight). In patients with diabetes mellitus appointment fluoxetine increases the risk of hypoglycemia and hyperglycemia - when its abolition. In connection with this dose of insulin and / or any other hypoglycemic LS used inside should be adjusted. Prior to the significant improvement in the treatment of patients should be under medical supervision. During treatment should refrain from receiving ethanol and occupations potentially hazardous activities that require attention and speed of mental and motor responses. The interval between the end of therapy inhibitors and the start of treatment with fluoxetine should be at least 14 days between the end of treatment with fluoxetine and starting therapy inhibitors - not less than 5 weeks. In liver and in old age, treatment should begin with 1 / 2 dose.
Interaction:
Enhance effects of alprazolam, diazepam, ethanol, and hypoglycemic LS. Increases in plasma concentration of phenytoin, tricyclic antidepressants, Maprotiline, trazodone 2-fold (to 50% lower dose of tricyclic antidepressants, while the application). Against the background of electroconvulsive therapy may develop prolonged seizures. Tryptophan enhances serotonergic properties of fluoxetine (increased agitation, restlessness, disorders of the gastrointestinal tract). MAO inhibitors increase the risk of serotonin syndrome (hyperthermia, chills, sweating, myoclonus, hyperreflexia, tremor, diarrhea, disturbances of coordination of movements, autonomic lability, agitation, delirium and coma). BOS, providing a depressing effect on the central nervous system, increase the risk of side effects and enhance the inhibitory effect on the central nervous system. In an application with the LS with a high degree of protein binding, especially with anticoagulants and digitoxin may increase plasma concentrations of free (unbound) medicines and an increased risk of adverse effects.
Description of the drug Prozac is not intended for purposes of treatment without the participation of a physician.
Trade name:
Prozac
International name:
Fluoxetine
Group Affiliation:
Antidepressant
Description of the active substance (INN):
Fluoxetine
Dosage form:
Capsules
Pharmacological Effects:
Antidepressive tool, a selective serotonin reuptake inhibitors. It improves mood, reduces tension, anxiety and fear, eliminates dysphoria. Does not cause orthostatic hypotension, sedation, nekardiotoksichen. Persistent clinical effect occurs within 1-2 weeks of treatment.
Indications:
Depression (regardless of the degree of depressive disorder - weak, moderate, severe), bulimia, anorexia, alcoholism, obsessive-compulsive disorder.
Contraindications:
Hypersensitivity, renal failure (CC less than 10 ml / min), expressed liver failure, suicidal tendencies, simultaneous reception of MAO inhibitors (in the previous 2 weeks), pregnancy, laktatsii.C caution. Diabetes mellitus, epileptic syndrome of different genesis and epilepsy (including history), Parkinson's disease, compensated renal and / or hepatic failure, cachexia.
Side effects:
From the nervous system: dizziness, headache, drowsiness or insomnia, lethargy, fatigue, asthenia, tremor, agitation, anxiety, suicidal tendencies (typical of patients with major depressive disorder), mania or hypomania. From the digestive system: loss of appetite, dry mouth or hygrostomia, nausea, diarrhea. Allergic reactions: skin rash, urticaria. Other: increased sweating, weight loss, decreased libido, systemic violations of the lung, kidney or liver, vaskulity.Peredozirovka. Symptoms: nausea, vomiting, a state of excitation, convulsions. Treatment: gastric lavage, the appointment of activated charcoal, in convulsions - anxiolytic LAN (tranquilizers), symptomatic therapy.
Dosage and administration:
Inside, depression starting dose - 20 mg / day 1 time in the morning if necessary, increase the weekly dose of 20 mg / day. The maximum daily dose - 80 mg in 2-3 doses. With bulimia, and for elderly patients - 60 mg in 3 divided doses, with obsessive-compulsive disorder - 20-60 mg / day. Maintenance therapy - 20 mg / day. Course of treatment - 3-4 weeks.
Cautions:
When treating patients with underweight anorectics should take into account the effects of (possible progressive loss of body weight). In patients with diabetes mellitus appointment fluoxetine increases the risk of hypoglycemia and hyperglycemia - when its abolition. In connection with this dose of insulin and / or any other hypoglycemic LS used inside should be adjusted. Prior to the significant improvement in the treatment of patients should be under medical supervision. During treatment should refrain from receiving ethanol and occupations potentially hazardous activities that require attention and speed of mental and motor responses. The interval between the end of therapy inhibitors and the start of treatment with fluoxetine should be at least 14 days between the end of treatment with fluoxetine and starting therapy inhibitors - not less than 5 weeks. In liver and in old age, treatment should begin with 1 / 2 dose.
Interaction:
Enhance effects of alprazolam, diazepam, ethanol, and hypoglycemic LS. Increases in plasma concentration of phenytoin, tricyclic antidepressants, Maprotiline, trazodone 2-fold (to 50% lower dose of tricyclic antidepressants, while the application). Against the background of electroconvulsive therapy may develop prolonged seizures. Tryptophan enhances serotonergic properties of fluoxetine (increased agitation, restlessness, disorders of the gastrointestinal tract). MAO inhibitors increase the risk of serotonin syndrome (hyperthermia, chills, sweating, myoclonus, hyperreflexia, tremor, diarrhea, disturbances of coordination of movements, autonomic lability, agitation, delirium and coma). BOS, providing a depressing effect on the central nervous system, increase the risk of side effects and enhance the inhibitory effect on the central nervous system. In an application with the LS with a high degree of protein binding, especially with anticoagulants and digitoxin may increase plasma concentrations of free (unbound) medicines and an increased risk of adverse effects.
Description of the drug Prozac is not intended for purposes of treatment without the participation of a physician.
Sunday, December 13, 2009
How to discuss sensitive issues with children
Sooner or later, every parent has to communicate with children to raise unpleasant and sensitive issues. For example, before the child is necessary to bring about such diseases as HIV infection, why should be afraid to talk and somewhere to go with strangers, talk about the dangers of smoking and alcohol consumption on sexual life ... How to do it right?
On whatever topic you choose to start a conversation that the child took the information and agreed to abide by the rules to ensure his safety, should:
1 - Find a real reason to start a conversation. For example, the subject of news, PSAs, or event in the life of a relative, friend - in the life of every man there are sad events and by no means always the child is with them to keep silent. Even better, if your son or daughter, he begins to talk, "You know, Mom, and in our school a boy found the tablets of ecstasy ...
2 - Do not threaten or intimidate the child and leave alone didactic tone. Statements like "That's going to linger on the streets at night - you need to attack," or "Mother is always right and good wishes to your mother, do not you go to these discos, the drugs in spiked water and offer a free to try, then you vtyaneshsya ! evoke a child only two feelings - a feeling of resentment and a sense of protest.
Children are not so stupid and simple as it seems to adults, they often really appreciate the danger and insults that adults can not see. And a sense of protest - "I'm not a little of what they did with me talk!" - The child is able to mess things up a lot of nonsense.
3 - Writing to understand a child that a house for him - a "safe harbor". What he can come to parents with any problems and troubles, and it will not criticize, condemn, punish, and vice versa - sympathize, help, and so on. The child must know that his parents love him - any and all times.
4 - Be honest with your child. Of course, so far as possible: because of age, children up to a certain time not able to fully understand some things. But do not lie, even the baby, that he, for example, should not talk to strangers, because it is evil wizards who can turn it into stone. It is better to say that the stranger can steal a child, ever take away from the house. Older kids can all be explained in more detail.
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On whatever topic you choose to start a conversation that the child took the information and agreed to abide by the rules to ensure his safety, should:
1 - Find a real reason to start a conversation. For example, the subject of news, PSAs, or event in the life of a relative, friend - in the life of every man there are sad events and by no means always the child is with them to keep silent. Even better, if your son or daughter, he begins to talk, "You know, Mom, and in our school a boy found the tablets of ecstasy ...
2 - Do not threaten or intimidate the child and leave alone didactic tone. Statements like "That's going to linger on the streets at night - you need to attack," or "Mother is always right and good wishes to your mother, do not you go to these discos, the drugs in spiked water and offer a free to try, then you vtyaneshsya ! evoke a child only two feelings - a feeling of resentment and a sense of protest.
Children are not so stupid and simple as it seems to adults, they often really appreciate the danger and insults that adults can not see. And a sense of protest - "I'm not a little of what they did with me talk!" - The child is able to mess things up a lot of nonsense.
3 - Writing to understand a child that a house for him - a "safe harbor". What he can come to parents with any problems and troubles, and it will not criticize, condemn, punish, and vice versa - sympathize, help, and so on. The child must know that his parents love him - any and all times.
4 - Be honest with your child. Of course, so far as possible: because of age, children up to a certain time not able to fully understand some things. But do not lie, even the baby, that he, for example, should not talk to strangers, because it is evil wizards who can turn it into stone. It is better to say that the stranger can steal a child, ever take away from the house. Older kids can all be explained in more detail.
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Friday, December 11, 2009
Kamasutra
Kama Sutra - the world's oldest treatise on love, in his collected knowledge, skills and wisdom of thousands of pairs! Posted this very valuable book Malla-naked Vatsyayana, an Indian sage who lived in the III-IV centuries AD.
Kama Sutra contains 35 chapters, collected in 7 sections, each of which is written by experts in the relevant field. Often referred to as:
Introduction (4 chapters) - on love in general, its place in human life and the classification of women.
On sexual union (10 chapters) - in-depth analysis of kisses, of various types of pre-weasels, orgasm, a list of sexual positions, oral sex, paraphilia, as well as the situation of a love triangle (three of a family - husband, wife and mistress of her husband).
Learn how to find a wife (5 chapters) - courtship and marriage.
On his wife (2 chapters) - as a wife should behave.
About the wives of other people (6 chapters) - mainly about seduction.
Prostitutes (6 chapters).
Learn how to charm others (2 chapters).
Interestingly, in India, quite common gifts in the form of books like Kamasutra, girls and young women, in order to help them discover themselves in terms of sexuality, to gain experience in the sensory area.
Nowadays Kamasutra - undoubtedly the most famous throughout the world book on the teachings of love. The name of the scientist of the treatise is so ingrained in our perception and everyday language, which has become an integral part of it. Pronouncing the word, Kama Sutra, we mean the tall, elegant, refined sexual relations. But often our knowledge is in question and is based on myths and misconceptions.
And it is not properly be considered as the Kama Sutra another, but, of course, ancient, western European tour of sex, which simply describes over a dozen different poses.
There is another myth, though the position described in Kamasutra are so complex technically, that without training them, and can not be used. However, it is not. In fact, do not necessarily have exclusive power or discharge of acrobatics to try to own all the subtleties of the teachings Indians.
The vast majority of such errors due to the fact that the West still does not have an analogue of the Kama Sutra. Western publications in the majority or simply pornography, or else more medical reference book, stuffed with various details in terms of anatomy, than a book about love. Agree, in this scenario a person would no longer be simply a desire to understand sex as art.
But in fact, many of us view sex as an exceptional way to meet the needs of the lowest, or, as an effective "weapon" to reproduce their own kind.
In contrast, the sexual act in the East with the sources is something secret, sacred, and the relationship between a man and a woman described in the books of highly artistic terms and words. And this break between our own language, and this fact, the language of sensory East, is simply amazing.
Kamasutra sex classes called "divine union".
Kamasutra - is the worship of a woman, a real Oda. In every word, addressed to a woman who sounds admiration and worship. A woman in the Kama Sutra has the largest number of rights, without her man is not tested and a third that can offer this amazing book.
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Kama Sutra contains 35 chapters, collected in 7 sections, each of which is written by experts in the relevant field. Often referred to as:
Introduction (4 chapters) - on love in general, its place in human life and the classification of women.
On sexual union (10 chapters) - in-depth analysis of kisses, of various types of pre-weasels, orgasm, a list of sexual positions, oral sex, paraphilia, as well as the situation of a love triangle (three of a family - husband, wife and mistress of her husband).
Learn how to find a wife (5 chapters) - courtship and marriage.
On his wife (2 chapters) - as a wife should behave.
About the wives of other people (6 chapters) - mainly about seduction.
Prostitutes (6 chapters).
Learn how to charm others (2 chapters).
Interestingly, in India, quite common gifts in the form of books like Kamasutra, girls and young women, in order to help them discover themselves in terms of sexuality, to gain experience in the sensory area.
Nowadays Kamasutra - undoubtedly the most famous throughout the world book on the teachings of love. The name of the scientist of the treatise is so ingrained in our perception and everyday language, which has become an integral part of it. Pronouncing the word, Kama Sutra, we mean the tall, elegant, refined sexual relations. But often our knowledge is in question and is based on myths and misconceptions.
And it is not properly be considered as the Kama Sutra another, but, of course, ancient, western European tour of sex, which simply describes over a dozen different poses.
There is another myth, though the position described in Kamasutra are so complex technically, that without training them, and can not be used. However, it is not. In fact, do not necessarily have exclusive power or discharge of acrobatics to try to own all the subtleties of the teachings Indians.
The vast majority of such errors due to the fact that the West still does not have an analogue of the Kama Sutra. Western publications in the majority or simply pornography, or else more medical reference book, stuffed with various details in terms of anatomy, than a book about love. Agree, in this scenario a person would no longer be simply a desire to understand sex as art.
But in fact, many of us view sex as an exceptional way to meet the needs of the lowest, or, as an effective "weapon" to reproduce their own kind.
In contrast, the sexual act in the East with the sources is something secret, sacred, and the relationship between a man and a woman described in the books of highly artistic terms and words. And this break between our own language, and this fact, the language of sensory East, is simply amazing.
Kamasutra sex classes called "divine union".
Kamasutra - is the worship of a woman, a real Oda. In every word, addressed to a woman who sounds admiration and worship. A woman in the Kama Sutra has the largest number of rights, without her man is not tested and a third that can offer this amazing book.
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How and where to learn a lonely girl
The Internet
Around the internet dating had the widespread belief that the web sites of acquaintances sit introverts suffer from complexes, for which the World Wide Web - last chance to find a life partner.
rogerklee
erickwal
But this is nothing more than a myth. Internet is so powerful and globally in almost all segments of the population that the online space today, you can meet anyone. Including adequate, successful and free men. On the Internet find each other thousands of people, if you reminisce, are certain to find such examples, and among his acquaintances.
ytah
idow
Make yourself a good photograph, pokreativnee fill out a questionnaire on several dating sites, and the result will not keep you waiting. But not limited to dating sites. Communicate on forums with the same interests, find boyfriend there fewer chances, but if that happens, you will unite not only the lyrical interest.
At work
If you rarely go to clubs, do not like to hang out and prefer to conduct most of their time at home, try to learn on the job.
blogodzee
kradiq
This is a very convenient option, because so you combine business with pleasure. The main thing you need to do - to present itself vividly before their male counterparts. Do yourself a new haircut, wear a little more sexy than usual, and add a note of his playful tone when communicating.
If you are confused by the prospect of office romance, then it is not necessary to flirt with men of your department. Turn its attention to other parts of your company, there may also be worthy candidates.
In the company of friends
Friendship Company - one of the most agreeable solutions to problems. In such companies, most people know each other, so the furnishings are arranged, including for new acquaintances.
Moreover, in this case, you can always count on the help of friends. So do not miss a single friendly Sabantui or even take the initiative to organize them.
The fitness centers
twerg
gocy
Fitness centers - has long been one of the most popular places for singles. Moreover, and girls, and boys learn there with a mutual activity. Connoisseurs even know which of these centers most "fish". But you first fit any more or less a big one.
Walk to the fitness room, and seeing someone who you like, start to engage in the vicinity. When fitnesist will take a break between his exercises, you can ask him to help you to hedge, for example, bench press. The usual situation for the gym - and together with the perfect opportunity for singles.
In supermarket
You may seem strange, but the supermarket, in fact, has excellent potential for new acquaintances.
Come across, again, completely different people and in large quantities.
nysony
torbek
If you go to the supermarket once a week and long standing in the wine department, pretending that it's difficult to determine the choice, it is possible to provoke a hardball interest on the part of men.
In the end, you yourself can contact you liked the man with the request to advise you on any drink. Judging by the reviews on some women's forums, works flawlessly.
The club
And why not? This is the easiest way to new relations. The club for this and go.
The only thing better than going to different clubs and not the luxury, because they tend to gather up the so-called hunters. one-night stand, sex for one night, without the commitment and desire to build a serious relationship.
Around the internet dating had the widespread belief that the web sites of acquaintances sit introverts suffer from complexes, for which the World Wide Web - last chance to find a life partner.
rogerklee
erickwal
But this is nothing more than a myth. Internet is so powerful and globally in almost all segments of the population that the online space today, you can meet anyone. Including adequate, successful and free men. On the Internet find each other thousands of people, if you reminisce, are certain to find such examples, and among his acquaintances.
ytah
idow
Make yourself a good photograph, pokreativnee fill out a questionnaire on several dating sites, and the result will not keep you waiting. But not limited to dating sites. Communicate on forums with the same interests, find boyfriend there fewer chances, but if that happens, you will unite not only the lyrical interest.
At work
If you rarely go to clubs, do not like to hang out and prefer to conduct most of their time at home, try to learn on the job.
blogodzee
kradiq
This is a very convenient option, because so you combine business with pleasure. The main thing you need to do - to present itself vividly before their male counterparts. Do yourself a new haircut, wear a little more sexy than usual, and add a note of his playful tone when communicating.
If you are confused by the prospect of office romance, then it is not necessary to flirt with men of your department. Turn its attention to other parts of your company, there may also be worthy candidates.
In the company of friends
Friendship Company - one of the most agreeable solutions to problems. In such companies, most people know each other, so the furnishings are arranged, including for new acquaintances.
Moreover, in this case, you can always count on the help of friends. So do not miss a single friendly Sabantui or even take the initiative to organize them.
The fitness centers
twerg
gocy
Fitness centers - has long been one of the most popular places for singles. Moreover, and girls, and boys learn there with a mutual activity. Connoisseurs even know which of these centers most "fish". But you first fit any more or less a big one.
Walk to the fitness room, and seeing someone who you like, start to engage in the vicinity. When fitnesist will take a break between his exercises, you can ask him to help you to hedge, for example, bench press. The usual situation for the gym - and together with the perfect opportunity for singles.
In supermarket
You may seem strange, but the supermarket, in fact, has excellent potential for new acquaintances.
Come across, again, completely different people and in large quantities.
nysony
torbek
If you go to the supermarket once a week and long standing in the wine department, pretending that it's difficult to determine the choice, it is possible to provoke a hardball interest on the part of men.
In the end, you yourself can contact you liked the man with the request to advise you on any drink. Judging by the reviews on some women's forums, works flawlessly.
The club
And why not? This is the easiest way to new relations. The club for this and go.
The only thing better than going to different clubs and not the luxury, because they tend to gather up the so-called hunters. one-night stand, sex for one night, without the commitment and desire to build a serious relationship.
Sunday, December 6, 2009
Impotence - We'll Won!
Impotence ... How many in this word. Someone suffering from this, someone is trying to turn it into a joke, anyone that is more convenient. But what would we not say that there is some concept of this concept in general. No. Today we will not go easy on the banal treatment of impotence or eliminate it. Let's look at it from a philosophical side. What is impotence, why they want to cure millions of men and what can be done in the end. Well, first, impotence is a male disease, a serious problem for the majority, but in my practice I have met a lot of people who fundamentally decided to put this notion of a point. That is, they forgot about him as such. And be honest, I think it could be very significant alternative to different kinds of suffering from the disease. What is the point? And the point is that people suffering from impotence focuses constantly on the disease. His day starts with a thought, damn, why is everyone so hard time? At a time when a person is "forgotten" about it not even remember her. In his mind completely different problem. However, this is just a psychological approach, a kind of test that can definitely affect the situation in general. If a person thinks constantly about the problem, then he would be attracted by it as at the level of thought. So when we think for example, where to get the money, we constantly are working on hundreds of ideas that our brain is trying to tell us, and eventually find it. But unlike my example with erectile dysfunction is more complicated, and it does not cease to bother you just because you think "That shit is not for me." My way to show you the other side of the coin. I will be brief, and may my secret you'll understand. But first, a response to the question is really whether you need a great erection, or is it just a fleeting desire, desire for sex, the desire to prove to someone that you are capable. There are many aspects of the course, but the basic idea in the competent management of your power of thought. Today everything, but I would like to tell a story. This story was told to me by a friend of mine. What was once one of the states in the United States rode a train which was carrying freezers and equipment. The train went 2 police officers. And so it happened that has been informed that that one of the freezers are not working correctly. That is no longer producing cold. Then one of the policemen decided to check what it was. The train stopped and the police approached the car from the freezer. He opened it, went inside and began to examine her. At this time the freezer door shut. The policeman was in a panic. He was seized by shock. He thought that he would die in it and began struggling to call his partner, to help him escape. But after more than 20 minutes while team-mate did not come. Then the police lost all hope of salvation. It seemed to him that he began to freeze, and his body was covered with ice. As a result, the police was killed in a closed freezer. When his partner pulled himself up and opened the door he saw his friend dead. He was shocked and did not understand why it happened. So, what is the moral of the story. Morality and meaning in the fact that the freezer was not working. She just was in the car, its easy to transport, but it was not even connected. The conclusion here is such that our power of thought capable of much. We even can not imagine how we can change our lives by only one power of thought. In the story, the policeman who died so scared that if he presented freezes. As a result, he "called the" death of ...
More interesting:
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More interesting:
Viagra Cialis Levitra
Abuse beer turns men in hermaphrodite
American demand from doctors three million for cured impotence
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