Monday, May 3, 2010

motley group

Moreover, the same researchers noticed that people with high levels of cholesterol in the blood rarely suffer various forms of dementia, including Alzheimer's disease.

It would seem contradictory information is obtained. A lot of cholesterol - good or bad? When the diagnostic capabilities of laboratory medicine grew, it became clear that cholesterol in its pure form in our bodies does not exist, that he has three sources and three component parts, drastically differing properties and functions.

Mad, Bad and good

As a lipophilic substance ("zhirolyubivym") cholesterol in the blood plasma does not dissolved. Consequently, in order to be transported, require specialized protein-carriers. They are called apolipoprotein B, and complex "cholesterol + transport protein" is called a lipoprotein. These same lipoprotein distinguish three classes: HDL (high-density lipoprotein, HDL), LDL (low density lipoprotein, LDL) and VLDL (very low density lipoproteins, VLDL).
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HDL, which for strong facilitation sometimes called the "good" cholesterol, are readily soluble in water, does not tend to precipitate. They transport the cholesterol from the cells of various organs in the biochemical laboratory of the body - the liver. There is cholesterol converted into bile acids and excreted through the intestines.

LDL, which, again, for a strong simplification called "bad cholesterol", is the main transport form of cholesterol in the body. They carry cholesterol to cells of the body, as well as between cells. Poorly soluble in water and are not a good tendency to precipitate. This high level of LDL and is considered one of the major risk factors for atherosclerosis.

VLDL - rather motley group, which got everyone who did not have enough seats in the first two groups. Synthesized mainly in the liver, and their function - carry cholesterol and triglycerides from the liver to other organs. VLDL could be called "evil" cholesterol, because they take an active part in the formation of atherosclerotic plaques, and deservedly considered the most atherogenic lipoproteins.

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