ED PRO TREATMENT

Revolutionary event in the treatment of erectile dysfunction was the appearance in 1996, the drug sildenafil citrate, has become known under the trade name "Viagra". This drug, taken orally in a tablet form, increased the effectiveness of treatment and provided an opportunity for general practitioners to help patients with ED. However, many men, especially with severe erectile dysfunction, diabetes, arterial hypertension, and patients who had undergone radical prostatectomy, is not fully satisfied with the existing treatment. In addition, the effect of sildenafil depends on eating and drinking, often victims of sexual components, which creates some problems with the planning of sexual intercourse. These circumstances lead to the fact that on average only 50% of patients taking sildenafil, intend to continue treatment.
Next approved the use of PDE5 inhibitor sildenafil has become after the drug "Cialis (tadalafil). In contrast, sildenafil the drug has a long half-life (17.5 h) and its pharmacokinetics is independent of food intake and alcohol. Thus, the duration of Cialis (36 h) allows comfortable with the so-called planning a sexual act and keep the spontaneity and romance of sexual relations. However, recent studies show that only 13% of patients with ED are interested in the duration of action of drugs and mainly interested in reliability (40%) and safety (40%) received therapy. In addition, some patients taking tadalafil, marked side effects such as back pain, and some of them these signs continue for as long as the drug acts. Cialis is available in a single dose (20 mg), which creates some problems with the correction of the therapy depending on the effectiveness and tolerability.
Thus, a certain number of patients dissatisfied with the previous treatment of ED, as well as a large number of patients with undiagnosed and untreated disorders of erection, in need of a new, more effective drugs. Ideal therapy for ED is noninvasive, ie, involve administration of oral medication, is a highly portable treatment, is equally effective in all populations. All the above requirements among the existing products in the best preparation "Levitra (vardenafil hydrochloride) - a new, highly efficient and the most potent inhibitor of PDE5. Vardenafil for the influence of sildenafil on PDE5 stronger in more than 10 times. Vardenafil has less compared with sildenafil effect on the light effect and smaller compared with sildenafil and tadalafil effect on spermatogenesis.
Vardenafil is rapidly absorbed, maximum concentration of drug in blood plasma is reached after an average of 30 minutes after oral administration. Duration of the drug, Levitra, 4-5 h, which is sufficient for full sexual intercourse, and does not result in the accumulation of the drug in humans. This is printsipialynym difference from tadalafil, a significant long half-life which is to cause harmful effects in the daily admission. The effectiveness of the drug did not affect food intake and alcohol.

The clinical study showed that vardenafil is highly effective (85-89%) and safe drug attraction ED. More powerful effect of this drug on PDE5 can be used not only in the general population, but when no other effective PDE5 inhibitors (sildenafil, tadalafil). The effectiveness of the drug, Levitra, patients with diabetes mellitus and after radical prostatectomy is 72%, and in patients previously unsuccessfully taking sildenafil - 62%.

Side effects while taking Levitra in most cases short-lived and insignificant.

Thanks to these properties of the drug as a rapid and pronounced effect, independent of food intake and alcohol, patients will be able to plan the sexual act at any convenient time. The product is available in three doses (5,10 and 20 mg), which allows a doctor to carry out correction therapy, depending on its effectiveness and tolerability. These and other differences from Viagra, such as the lack of effect of tachyphylaxis (loss of efficiency in the long-term therapy), give great hope for long-term treatment of ED.
Thus, existing today drugs to treat erectile dysfunction can get positive results in most patients. Unfortunately, leaving a portion of ED patients who have either ineffective pharmacotherapy. In these patients used other treatments (combined oral and intrakavernoznaya therapy vakuumterapiya, surgical treatments).